Product Overview: Methylation of histone H3 at lysine 79 is catalyzed by Dot1 in mammalian cells. Intergenic H3 (mono-methyl K79) is a mark of enhancer regions and may provide unique binding surfaces along the chromatin fibre to stabilize interactions between enhancers and their target promoters. H3 (di-methyl K79) and H3 (tri-methyl K79) are also widespread […]
- Histone Methylation Kits and Assays
EpiSeeker Histone H4 (mono-methyl K20) Quantification Kit (Colorimetric)
Product Overview: Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (mono-methyl K20) is involved in the maintenance of the proper higher order structure of DNA and is consequently essential for chromosome condensation. It is also involved in gene silencing. EpiSeeker Histone H4 […]
EpiSeeker Histone H4 (pan-methyl K20) Quantification Kit (Fluorometric)
Product Overview: Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (mono-methyl K20) is involved in the maintenance of proper higher order structure of DNA and is consequently essential for chromosome condensation, as well as functioning in gene silencing. H4 (di-methyl K20) has […]
EpiSeeker Histone H4 (pan-methyl K20) Quantification Kit (Colorimetric)
Product Overview: Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (mono-methyl K20) is involved in the maintenance of proper higher order structure of DNA and is consequently essential for chromosome condensation, as well as functioning in gene silencing. H4 (di-methyl K20) has […]
EpiSeeker Histone H4 (tri-methyl K20) Quantification Kit (Fluorometric)
Product Overview: Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (tri-methyl K20) acts as a passive feature or structure determinant for chromatin degradation and release, as well as being an epigenetic marker of early apoptosis. H4 (tri-methyl K20) is also considered as […]