Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer (1,2). It is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene reg4ation.
- Histones
Histone H2B Human, Recombinant
Histone H2B combines with Histone H2A to form the H2A-H2B heterodimer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. (1,2) Histone H2B is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene reg4ation.
Histone H2A Human, Recombinant
Histone H2A combines with Histone H2B to form the H2A-H2B heterodimer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. (1,2) Histone H2A is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene reg4ation.
Histone H1 Human, Recombinant
Histone H1 acts on the linker region of polynucleosome DNA to condense the chromatin into structures of ~30 nm (1). It is not necessary for octamer or nucleosome core particle formation. Eight different Histone H1 proteins have been identified in the human genome (2). Histone H10 is a non replication-dependent histone that is highly expressed […]