The EpiTect MSP Kit enables highly reliable and accurate methylation-specific PCR. The kit includes the novel, genetically engineered HotStarTaq d-Tect Polymerase, which increases primer extension specificity for better methylation-specific primer discrimination by preventing elongation of mismatched bases at the 3′ end of the primers used for MSP. This innovative method ensures highly specific MSP results compared with standard Hot-Start Polymerase.
- DNA Methylation Specific PCR
CpGenome™Universal Methylated DNA
CpGenome™ Universal Methylated DNA is enzymatically methylated human male genomic DNA. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) or with amplification primers. It can be used as a methylation-positive control for gene methylation studies.
CpGenome™Fast DNA Modification Kit
The CpGenome™ Fast DNA Modification Kit contains reagents required to perform a bisulfite modification on a DNA sample including DNA isolation columns for easy and efficient recovery of bisulfite treated DNA.
CpGenome™ Universal Unmethylated DNA
CpGenome™ Universal Unmethylated DNA Set provides 2 separate genomic DNA controls for gene methylation studies. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) and can be subsequently used as an unmethylated DNA control for gene methylation studies.
CpG WIZ®SOCS1 Amplification Kit
Methylation of cytosines located 5′ to guanosine is known to have a profound effect on the expression of several eukaryotic genes (Bird, 1992). In normal cells, methylation occurs predominantly in CG-poor regions, while CG-rich areas, called CpG islands, remain unmethylated. Aberrant methylation of normally unmethylated CpG islands has been documented as a relatively frequent event […]