Product Overview: Methylation of histone H3 at lysine 79 is catalyzed by Dot1 in mammalian cells. Intergenic H3 (mono-methyl K79) is a mark of enhancer regions and may provide unique binding surfaces along the chromatin fiber to stabilize interactions between enhancers and their target promoters.
EpiSeeker Histone H3 (mono-methyl K79) Quantification Kit (Colorimetric) (ab115083) allows the user to specifically measure global mono-methylation of histone H3-K79 colorimetrically using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.
View EpiSeeker Histone H3 (mono-methyl K79) Quantification Kit (Colorimetric) on Abcam’s website