Product Overview: Methylation of histone H3 at lysine 36 seems to be coupled to the proces of active transcriptional elongation and it is enriched towards the 3′ end of target genes. However, when present within protein-coding regions it prevents inappropriate transcriptional initiation of intragenic sequences. H3 (mono-methyl K36) is commonly found together with H3 (di-methyl K27) and associated with transcriptionally silenced genes. However, H3 (di-methyl K36) and H3 (tri-methyl K36) are generally associated with transcriptionally active genes.
EpiSeeker Histone H3 (pan-methyl K36) Quantification Kit (Colorimetric) (ab115081) allows the user to specifically measure global mono-, di-, and tri-methylation of histone H3-K36 colorimetrically using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.
View EpiSeeker Histone H3 (pan-methyl K36) Quantification Kit (Colorimetric) on Abcam’s website