Product Overview: Methylation of histone H3 at lysine 4 by Methyl transferases such as SET1, SET7/9, MLL and Trx among others occurs in mammals in several distinct genomic distributions. In mammals, H3(mono-methyl K4) is associated with silenced euchromatin regions whereas H3(di-methyl K4) and H3(tri-methyl K4) is associated with transcriptionally active euchromatin regions.
EpiSeeker Histone H3 (pan-methyl K4) Quantification Kit (Colorimetric) (ab115058) allows the user to specifically measure global mono-, di-, and tri-methylation of histone H3-K4 colorimetrically using a variety of mammalian cells (human, mouse, etc.) including fresh and frozen tissues, cultured adherent and suspension cells.
View EpiSeeker Histone H3 (pan-methyl K4) Quantification Kit (Colorimetric) on Abcam’s website