Product Overview: Methylation of histone H3 at lysine 27 has an important role in transcription repression and it is catalyzed by G9a and Polycomb Groups enzymes such as EZH2. In particular, try-methylation of histone H3 (H3(try methyl K27)) is a facultative heterochromatin mark, which promotes the recruitment of polycomb group proteins for gene silencing. Increased global histone H3 (tri methyl K27) is also found to be involved in some pathological processes such as cancer progression.
EpiSeeker Histone H3 (tri methyl K27) Assay Kit (In Situ) (ab115045) allows the user to specifically measure histone H3-K27 tri-methylation in situ using cultured adherent cells in a quick and efficient procedure which can be finished within 3 hours.
View EpiSeeker Histone H3 (tri methyl K27) Assay Kit (In Situ) on Abcam’s website