You’ve heard before that timing is everything, and this is doubly true in developmental biology. New research out of Fuchou Tang’s lab (Peking University, Beijing) singles in on the timing of methylation changes during embryonic development, and exposes the delicate epigenetic dance of global demethylation and targeted remethylation. Tang’s lab is no stranger to embryonic […]
- Developmental Biology
CRISPR-Cas9 Embryo Editing…….Of Mice and Men!
Presumably after a day spent in a local tavern instead of writing and editing verse, the famous Scottish poet Robert Burns noted that “The best laid schemes of mice and men, Often go awry”. However, a new study of genome editing in the embryos of mice and men led by Kathy K. Niakan (Francis Crick […]
Histone Modification Imaging Pr-EDICTS Stem Cell Fate
Will it rain? Will my team win? Will I get that grant? There are instances where a glance into a fortune-teller’s crystal ball could definitely give you the upper hand. Although the crystal ball is a myth, researchers from the lab of Prabhas V. Moghe (Rutgers University, New Jersey, USA) have recently developed a means […]
Key Factors that Mend Broken Hearts
Jimmy Ruffin once asked, “What becomes of the broken hearted?” and the answer is normally found on a barstool or at the bottom of an ice cream tub. But for those suffering from the much more visceral consequences of a heart attack, the therapeutic avenues down which they can travel are more limited and less […]
At Risk of Autistic Offspring? Sperm DNA Methylation May Hold the Answer
Finding the origin of complex disease is no easy task but now it seems a seminal breakthrough has occurred. Andrew Feinberg and team at the John Hopkins University Center for Epigenetics have found a DNA methylation pattern in the sperm of fathers with an increased risk of fathering autistic children that is also present in brains […]