We’re halfway through 2010, so we’ve decided to take a look back at some of the best epigenetics publications we’ve covered so far this year. Here are some of our favorite Chromatin headlines.
Histone Mods and Alternative Splicing
This publication might have popped up in the mainest of mainstream journals, but the focus is all about alternatives…splicing that is. It’s always great to see the interplay of regulatory mechanisms, in this case histone modifications affecting alternative splicing so we couldn’t resist.
February 8, 2010 Histone Mods Choose Alternative Splicing Lifestyle
Memory Formation
The idea of histone modifications impacting our memory? These were a no-brainer.
March 17, 2010 Thank Histone Methylation for the Memories
May 6, 2010 Forgetting Things? Better Acetylate Your H4K12
Chromatin Remodeling by CpG Islands
We read a ton about the methylation action in CpG Islands, so it’s always nice when we read evidence highlighting that there’s more to CpGs than a CH3. These two pubs capture how unmethylated CpG islands can play a pivotal role in chromatin architecture.
April 28, 2010 CpG Islands Tackle Chromatin Remodeling Project
Nucleosome Positioning
Sure we might seperate topics like histones, chromatin, and DNA methylation into discreet areas on our site, but that’s really just to keep things tidy. The reality is that there’s a lot of interplay in epigenetic mechanisms. These two papers were picked to highlight this.
February 1, 2010 Methylation Puts Nucleosomes in the Hot Seat
June 7, 2010 Unscrambling Nucleosome-DNA Methylation Relations