Zymo-Spin™ ChIP Kits Give Chromatin Immunoprecipitations the Run-aroundFebruary 5, 2014After an extensive development and beta-testing process, the innovators at Zymo Research have unveiled the new Zymo-Spin™ ChIP Kit, which provides a whole new twist to standard chromatin precipitations. Special Discount to EpiGenie Readers: Get 20% OFF and a free “Blame It On My Epigenetics” T-shirt with every purchase of Zymo-Spin™ ChIP Kit (Catalog No. […]
Three Dimensional Chromatin & DNA Replication with Dr. David GilbertFebruary 3, 2014Dr. David Gilbert discusses the ins and outs of 3-D chromosome folding, DNA replication and the highly dynamic cell nucleus. 3-D Chromatin and DNA Replication There’s no question. The thing that I’m most excited about is the uncanny alignment between three dimensional chromatin confirmation maps and replication timing. The alignment is the greatest alignment that […]
The New Players in Epigenetic Reprogramming with Dr. Wolf ReikFebruary 3, 2014Dr. Wolf Reik discusses the latest advances in epigenetic reprogramming, and what those new discoveries might lead to. The New DNA Methylation Landscape So it’s become apparent in the last two years, I guess, that there is this process of genome-wide epigenetic reprogramming which occurs naturally in germ cells, early embryo stem cells, et cetera, […]
Webinar: Mechanisms of Epigenetic Regulation in Stem Cells and DevelopmentJanuary 31, 2014Dr. Alexander Meissner discusses the roles of epigenetic mechanisms in stem cells and development. Cytosine methylation in mammals is an epigenetic modification that is largely restricted to CpG dinucleotides and serves multiple critical functions including stable repression of target promoters, maintaining genomic integrity, establishing parent-specific imprinting patterns, and silencing endogenous retrotransposon activity. In somatic tissues, […]
Up In Smoke: Nicotine’s Epigenetic ConsequencesJanuary 22, 2014As anyone who has tried to kick a pack-a-day cigarette habit can attest, nicotine is bad news. The jitters and surly attitude are bad enough, but according to a new investigation, fetal nicotine exposure also does some pretty insidious epigenetic damage. Daniel Hardy and a talented team Western University (Canada) have revealed a chromatin mechanism that […]