EpiGenie Guide: ChIP Antibody ValidationFebruary 11, 2013If you can find a ChIP Grade or ChIP Validated antibody, then you’ve got a head start. But there’s no reason to stress if you can’t. Leave that for the data analysis part of your experiments (only kidding). A quick check of the spec sheet of any antibody can reveal lots of useful info. Here […]
EpiGenie 5hmC Technology GuideOctober 31, 2012A couple of years ago, researchers keen to analyze 5-hmC had a couple of options, but those early approaches couldn’t quite satisfy all of their increasing demands. Fast-forward a bit and it’s a very different story. Today there’s a plethora of options, each with its own strengths and weaknesses. As a result, one of the […]
Guide: Key Restriction Enzymes for DNA Methylation AnalysisOctober 22, 2012Enzymes and, in particular, restriction enzymes have been invaluable assistants in the laboratory for decades, so it is not surprising that they have been instrumental in driving discoveries in epigenetics-related research as well. Enzymatic manipulation of methylated DNA has seen a tremendous amount of innovation over the last 30 years, making these DNA modifying enzymes great […]
Free White Paper: Histone Acetylation and Methylation – Epigenetic Modulators of Gene ExpressionSeptember 26, 2012Histone acetylation and methylation are important cellular processes, but it can be hard keeping track of the structural ups and downs from HATs and HDACs. This free white-paper provides an informative, concise review of the key players in histone acetylation and methylation and their impact on specific residues. Download here >>>
Guide: Considerations for Choosing Effective ChIP AntibodiesAugust 24, 2012 With the expertise of Upstate® and Chemicon®, EMD Millipore has developed a comprehensive line of kits, assays, and antibodies for ChIP, so we understand the importance of choosing the right antibody for your ChIP experiment. In this guide, our research experts will share critical considerations for selecting an effective ChIP antibody. Download Print-Friendly […]
Guide: Quick Tips for ChIP BeginnersJuly 17, 2012 At Abcam we run quite a few ChIP assays and we interact with customers that run even more than us. Lately, we’ve noticed that more researchers are turning to ChIP for the first time as gene regulation studies continue to grow. So we thought we’d share a couple of quick tips for various aspects of […]
Guide: Simple Tips to Boost Your Bisulfite-Based ApplicationsJuly 11, 2012 Bisulfite conversion remains a key player in almost every study involving DNA methylation. Since DNA methylation is emerging as a key mechanism in a diverse range regulator processes and disease mechanisms, many researchers new to the field are turning to bisulfite-based analyses that might not be experts in the approach. We’ve been optimizing bisulfite […]
