Start stocking the miRNA-29b in your medicine cabinet. A group of researchers from The Ohio State University recently cranked out some great data demonstrating how miRNAs work to regulate DNA methylation in acute myeloid leukemia (AML), outlining a potential therapeutic use of mir-29b. The study reveals how miR-29b works by targeting DNA Methyltransferases (DNMTs), the […]
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PatMAn and the Magnificent Seven Methylation Classifiers
It seems pattern recognition and supervised learning techniques are being applied to epigenetics research a lot nowadays. These advanced computational techniques that have proven useful in everything from homeland security to financial modeling are lending a hand to some of the challenges in epigenetics research. Recently we’ve seen them applied to miRNA discovery and target […]