Product Overview: DNMT1 (DNA (cytosine-5)-methyltransferase 1) belongs to the DNMT family, responsible for methylation of CpG islands in the genome. DNMT1 preferably methylates cytosines located in hemimethylated DNA and it associates with DNA replication sites in S-phase. The selective inhibition of DNMT1 may lead to demethylation and expression of silenced tumor suppressor genes. Thus, the […]
- DNA Methyltransferase Kits and Assays
EpiSeeker DNMT3B Inhibitor Screening Assay Kit
Product Overview: DNMT3B (DNA (cytosine-5)-methyltransferase 3B) belongs to the DNMT family, it is required for genome de novo methylation and it is essential for establishment of DNA methylation patterns during development. The selective inhibition of DNMT3B may lead to demethylation and expression of silenced tumor suppressor genes. Thus, the selective DNMT3B inhibitors could be a […]
EpiSeeker DNMT Activity Quantification Kit (Colorimetric)
Product Overview: DNMT (DNA methylases) is a family of enzymes responsible for the addition of methyl groups on the cytosine ring at the 5′ position of a CpG dinucleotide. The DNMT family is required for the establishment and maintenance of DNA methylation patterns. EpiSeeker DNMT Activity Quantification Kit (Colorimetric) (ab113467) allows the user to colorimetrically […]
EpiSeeker DNMT Activity Quantification Kit (Fluorometric)
Product Overview: DNMT (DNA methylases) is a family of enzymes responsible for the addition of methyl groups on the cytosine ring at the 5′ position of a CpG dinucleotide. The DNMT family is required for the establishment and maintenance of DNA methylation patterns. EpiSeeker DNMT Activity Quantification Kit (Fluorometric) (ab113468) allows the user to fluorometrically […]
EpiSeeker DNMT1 Assay Kit
Product Overview: DNMT1 (DNA (cytosine-5)-methyltransferase 1) belongs to the DNMT family, responsible for methylation of CpG islands in the genome. DNMT1 preferably methylates cytosines located in hemimethylated DNA and it associates with DNA replication sites in S-phase. EpiSeeker DNMT1 Assay Kit (ab113469) allows the user to quickly and consistently measure the amount of DNMT1. The […]