Product Overview: DNMT3A (DNA (cytosine-5)-methyltransferase 3A) belongs to the DNMT family, and it is required for genome wide de novo methylation and it is essential for the establishment of DNA methylation patterns during development. EpiSeeker DNMT3A Assay Kit (ab113470) allows the user to quickly and consistently measure the amount of DNMT3A. The kit is ready-to-use […]
- DNA Methyltransferase Kits and Assays
EpiSeeker DNMT3B Assay Kit
Product Overview: DNMT3B (DNA (cytosine-5)-methyltransferase 3B) belongs to the DNMT family, it is required for genome de novo methylation and it is essential for establishment of DNA methylation patterns during development. EpiSeeker DNMT3B Assay Kit (ab113471) allows the user to quickly and consistently measure the amount of DNMT3B. The kit is ready-to-use and provides all […]
EpiSeeker DNA demethylase (total) Activity Quantification Assay Kit
Product Overview: DNA methylation plays an essential role in biological processess through repression of transcription, while DNA demethylation is necessary, on the other hand, for epigenetic reprogramming of these genes. Active demethylation of DNA requires specific demethylase participation such as from MBD2. EpiSeeker DNA demethylase (total) Activity Quantification Assay Kit (ab113472) allows the user to […]
EpiSeeker MBD2 Binding Activity Quantification Assay Kit
Product Overview: MBD2 (methyl-CpG binding domain protein 2) belongs to a family of MBD domain containing proteins. This family of proteins associates with heterochromatin by their interaction with methylated DNA at CpG islands, and appear to ‘read’ and ‘translate’ the DNA methylation signal into transcriptional repression by recruiting silencing complexes and histone deacetylases among other […]