Pre-miR miRNA Precursor Molecules are small, chemically modified double-stranded RNA molecules designed to mimic endogenous mature miRNAs. These ready-to-use miRNA mimics, which are similar to, but not identical to siRNAs, can be introduced into cells using transfection or electroporation parameters similar to those used for siRNAs. They enable detailed study of miRNA biological effects via […]
- miRNA Inhibition
miRCURY LNA™ microRNA Knockdown Probes
miRCURY LNATM microRNA Knockdown Probes are high-affinity LNA-enhanced probes for specific in vitro knockdown of microRNAs. Featuring minimal cytotoxicity and high biological stability. Effective and sequence-specific antisense inhibition of microRNAs Probes available for all known microRNAs Superior biological stability Minimal cytotoxicity Compatible with standard cell transfection methods Available pre-labeled with fluorescein for estimation of transfection efficiency […]
miRCURY LNA™ knockdown probe – ready to label
Pre-designed miRCURY LNA microRNA Knockdown Probes are available for all known microRNAs in invertebrates, vertebrates and plants as registered and annotated in the miRNA registry (miRBase) at The Wellcome Trust Sanger Institute. Effective and sequence-specific antisense inhibition of microRNA. Minimal cytotoxicity. Compatible with standard cell transfection methods. Increased biological stability
miRCURY LNA™ Knockdown Control Probes
miRCURY LNATM Negative control probes for quality assessment of your in vitro miRCURY LNA knockdown experiment Similar in probe length and LNA design to our miRCURY LNA microRNA Knockdown Probes No homology to any known microRNA or mRNA sequences in mouse, rat or human Coverage We currently offer two pre-designed miRCURY LNA Knockdown Control Probes: Scramble-miR […]
In vivo LNA microRNA Knockdown Probes
Highly specific and biologically stable LNA-enhanced knockdown probes for in vivo inhibition of microRNAs. Effective and sequence-specific antisense in vivo inhibition of microRNAs Superior serum stability and nuclease resistance Low toxicity Complete phosphorothioate backbone Available with fluorescein-label or conjugated to cholesterolZ Features: Exiqon uses empirically developed tools to design optimal LNA microRNA in vivo knockdown […]