miRCURY LNATM microRNA Knockdown Probes are high-affinity LNA-enhanced probes for specific in vitro knockdown of microRNAs. Featuring minimal cytotoxicity and high biological stability.
- Effective and sequence-specific antisense inhibition of microRNAs
- Probes available for all known microRNAs
- Superior biological stability
- Minimal cytotoxicity
- Compatible with standard cell transfection methods
- Available pre-labeled with fluorescein for estimation of transfection efficiency
Features:
The miRCURY LNA microRNA Knockdown Probes have been designed using Exiqon’s in-house design software ensuring optimal placement of the LNA nucleosides in the probe. The probes are designed to have high sequence specificity, low secondary structure and minimal self-annealing.
Coverage:
Pre-designed miRCURY LNA microRNA Knockdown Probes are available for all known microRNAs in invertebrates, vertebrates and plants as registered and annotated in the microRNA registry (miRBase) at the Wellcome Trust Sanger Institute. Five nmoles of probe is shipped in sterile RNase-free water, allowing direct application in standard transfection protocols. All probes are available as ready-to-label or as 3′ or 5′ pre-labeled probes (fluorescein- or amino-labeled).
Note: miRCURY LNA microRNA Control Knockdown probes for quality control of your knockdown experiments are also available.
View miRCURY LNA™ microRNA Knockdown Probes on Exiqon’s website