Product Overview: Protein-DNA interactions play a critical role for cellular functions such as signal transduction, gene transcription and epigenetic silencing. Identifying the genetic targets of DNA binding proteins and knowing the mechanishm of protein-DNA interaction is importatn for understanding cellular processes. EpiSeeker DNA-Protein Binding Assay Kit (Fluorometric) (ab117140) allows the user to investigate direct protein-DNA […]
- Abcam
EpiSeeker ChIP Kit – Histone H3 (methyl K9)
Product Overview: The position of the histone H3 at lysine 9 (H3 (K9)) is important for epigenetic regulation of genes, as it can be either methylated or acetylated. It has been demonstrated that switching H3(acetyl K9) to methylation on H3 (methyl K9) leads to chromatin gene silencing in many organisms. Thus, identification of genes silenced […]
EpiSeeker ChIP Kit – Histone H3 (tri-methyl K9)
Product Overview: The position of the histone H3 at lysine 9 (H3 (K9)) is important for epigenetic regulation of genes, as it can be either methylated or acetylated. It has been demonstrated that switching H3(acetyl K9) to methylation on H3 (methyl K9) leads to chromatin gene silencing in many organisms. H3 (tri-methyl K9) is a […]
EpiSeeker Histone H3 (tri-methyl K36) Quantification Kit (Fluorometric)
Product Overview:Methylation of histone H3 at lysine 36 seems to be coupled to the proces of active transcriptional elongation and it is enriched towards the 3′ end of target genes. However, when present within protein-coding regions it prevents inappropriate transcriptional initiation of intragenic sequences. In particular, H3 (tri-methyl K36) is associated with transcriptionally active genes. […]
EpiSeeker Histone H3 (pan-methyl K36) Quantification Kit (Colorimetric)
Product Overview: Methylation of histone H3 at lysine 36 seems to be coupled to the proces of active transcriptional elongation and it is enriched towards the 3′ end of target genes. However, when present within protein-coding regions it prevents inappropriate transcriptional initiation of intragenic sequences. H3 (mono-methyl K36) is commonly found together with H3 (di-methyl […]