DNA Degradase™ from Zymo Research is a nuclease mix that quickly and efficiently degrades DNA to its individual nucleotide components. DNA Degradase™ is ideal for whole-genome DNA methylation analysis by a number of downstream applications (i.e., HPLC, TLC, etc.). Digestion with the enzyme is performed via a one-step procedure that is faster and simpler than […]
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DNA Degradase Plus™
DNA Degradase Plus™ from Zymo Research is a nuclease mix that quickly and efficiently degrades DNA to its individual nucleoside components. Since nucleosides lack negatively charged phosphate, DNA Degradase Plus™ is ideal for whole-genome DNA methylation analysis by LC/MS. Digestion with the enzyme is performed via a one-step procedure that is faster and simpler than […]
5-Methylcytosine & 5-Hydroxymethylcytosine DNA Standard Set
The 5-Methylcytosine & 5-Hydroxymethylcytosine DNA Standard Set is a set of three DNA standards that are linear dsDNA, 897 bp, and have the same sequence. The only difference is that each contains either 100% unmodified cytosines, 5-methylcytosines, or 5-hydroxymethylcytosines (see figure). Since the sequence and extent of cytosine modification is known, this DNA standard set […]
Quest 5-hmC Detection Kit™
The Quest 5-hmC Detection Kit™ from Zymo Research allows for sequence specific detection of 5-hydroxymethylcytosine within DNA using a simple and efficient reaction setup. Utilizing a robust and highly specific 5-hmC Glucosyltransferase enzyme, 5-hydroxymethylcytosine in DNA is specifically tagged with a glucose moiety yielding a modified base, glucosyl-5-hydroxymethylcytosine. Product Highlights: Method to specifically distinguish 5-hydroxymethylcytosine […]