In Greek mythology, the fates forge the strings of life that control our lives and choose the moment of its end. We mere mortals yearn for such powers and we are now one step closer to the light thanks to an optogenetic epigenome editing system that lets you write and erase DNA methylation to control […]
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Are you crazy for CRISPR-Cas9? Are you gaga for in vivo gene editing? You should probably get out more, but in the meantime we have just the study for you. A new Nature Biotechnology study from the lab of Jennifer A Doudna has described a major step toward the in vivo application of CRISPR-Cas9-mediated gene […]
For those living in the more Northern climes, this is just about the time when you would give nearly anything for a sunny pool party. When it comes to pool parties, CRISPR turns out to be a pretty good host, but with one important caveat – CRISPR pool parties tend to be life-or-death affairs. Pooled […]
The post-holiday party period is always an excellent time to reflect that there can always be too much of a good thing. Whether it’s cookies, champagne, or Bing Crosby, sometimes you just need an off-switch. The same can be true of Cas9 – leaving it turned on after your gene editing is done, or leaky […]
Just like kids during the holidays, young stem cells have all the fun with their fancy new CRISPR-themed gene editing gifts, while their older, wiser, more differentiated counterparts keep getting nothing but coal. (Well technically carbon nanotubes, but elementally the same). This neglect is partly the fault of more differentiated cells themselves; stodgy as they are, […]