Human recombinant HDAC3/NCOR1 produced in insect cells
Background Information:
Unlike other class I HDAC enzymes, HDAC3 is found in co-repressor complexes with the SMRT/N-CoR proteins. HDAC3 contains a unique domain structure which includes both nuclear localization and nuclear export sequences. HDAC3 has been implicated in cancer, as HDAC3 inhibitors produce anti-proliferative effects in various cancer cells. It may also play a role in heart disease, which may involve deacetylation of MEF2
View HDAC3/NCOR1 complex human recombinant on Millipore’s website