Human recombinant HDAC2 (1-488) (His-tag) produced in insect cells
Background Information:
Histone deacetylase 6 (HDAC6) is member of the class II HDAC family, shich share significant sequence homology to the yeast HDA1 protein. HDAC6 is unique among human HDACs in having two full deacetylase domains. As a tubulin deacetylase, HDAC6 may act to promote autophagic clearing of huntingtin aggregates and retard HIV1 infection, but may also promote invasive motility in tumor cells.