Epigenetics Controls Reading of Genetic Code Epigentics refers to high level information residing above the genetic code. While each cell in the body is equipped with the same genetic manual, epigenetic instructions tell cells how to make a difference. These instructions determine the access to pages with genetic information by directing the way the DNA […]
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Epigenetic Regulation
It has been over 30 years since DNA methylation was first postulated to be a heritable modification capable of influencing gene expression35,70. The addition of a methyl-group to the cytosine base does not change the primary DNA sequence and is therefore considered to be an epigenetic modification, literally meaning to act “on top of” or “in addition” […]
Epigenetics Background
The field of epigenetics, transcending genetics, genomics, and molecular biology, is now poised to be the vanguard of biological science. The rise of epigenetics marks a maturation of the field, which only 50 years ago was given its name and a vague definition, but is now a dynamic discipline, challenging and revising traditional paradigms of […]
EpiGenie Stem Cell Epigenetics Review
We’re big fans of stem cell research, the vast potential it represents and the close connection it has to epigenetics. Apparently we aren’t alone either, judging by the avalanche of top-notch papers that regularly cross our monitors. We’ve even give serious consideration to launching another site just to be able cover the area properly (StemGenie, […]
DNA and Histone H3K9 Methylation Often Work Alone
Nature is a master of using specific tools for specific jobs, so it’s not too surprising that DNA methylation and SETDB1/H3K9 methylation work on different sets of genes, as University of British Columbia researchers report. But occasionally those tools are more like a Swiss Army knife, like SETDB1, which also methylates H3K9s near endogenous retroviruses […]