Active Motif’s MethylCollector™ Ultra offers a fast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA. MethylCollector Ultra is based on the Methylated CpG Island Recovery Assay (MIRA) which uses a MBD2b/MBD3L1 protein complex for improved enrichment of CpG dinucleotides. Enriched DNA can be used in many downstream applications, such as […]
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Chromatrap® ChIP Kits
The traditional ChIP methods, based on agarose or magnetic beads, involve many steps of separation, pipetting and re-suspension. These sequences can either be done by magnetism or centrifugation, which are repetitive and prone to errors. Chromatrap® is a new technology that offers a quicker, easier and more efficient way of undertaking chromatin immunoprecipitation assays. These kits […]
EZ-Magna ChIP™ HT96 Chromatin Immunoprecipitation Kit
The EZ-Magna ChIP HT96 kit allows the performance of chromatin Immunoprecipitation in a 96-well plate-based format. This reliable streamlined approach works for both cells and tissues and can be performed using either a multi-channel pipette or an automated liquid handling instrument. Each kit includes a complete set of validated, quality controlled reagents, positive and negative […]
Magna ChIP™ HT96 Chromatin Immunoprecipitation Kit
The Magna ChIP HT96 kit allows the performance of chromatin Immunoprecipitation in a 96-well plate-based format. This reliable streamlined approach works for both cells and tissues and can be performed using either a multi-channel pipette or an automated liquid handling instrument.Each kit includes a complete set of validated, quality controlled reagents, plus a detailed protocol. […]
Hydroxymethyl Collector
The Hydroxymethyl Collector™ Kit is designed to detect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation. The Hydroxymethyl Collector kit utilizes a β-glucosyltransferase enzyme to transfer a modified glucose moiety to 5-hydroxymethylcytosine residues in double-stranded DNA. This modified glucose is then used to chemically attach a biotin conjugate for capture and enrichment with streptavidin […]