Product Overview: Methylation of histone H3 at lysine 9 (K9) mediates heterochromatin formation by forming a binding site for HP1 and also participates in silencing expression at euchromatic sites. Moreover, presence of H3 (methyl K9) positively correlates with DNA methylation. EpiSeeker Histone H3 (methyl K9) Assay Kit (In Situ) (ab115047) allows the user to specifically […]
- Histone Methylation Kits and Assays
EpiSeeker Histone H3 (methyl K4) Assay Kit
Product Overview: Methylation of histone H3 at lysine 4 by Methyl transferases such as SET1, SET7/9, MLL and Trx among others occurs in mammals in several distinct genomic distributions and may serve as a global epigenetic mark in euchromatin. H3 (methyl K4) also appears to have an inverse correlation to allele-specific DNA methylation. EpiSeeker Histone […]
EpiSeeker Histone H3 (methyl K9) Assay Kit
Product Overview: Methylation of histone H3 at lysine 9 (K9) mediates heterochromatin formation by forming a binding site for HP1 and also participates in silencing expression at euchromatic sites. Moreover, presence of H3 (methyl K9) positively correlates with DNA methylation. EpiSeeker Histone H3 (methyl K9) Assay Kit (ab115049) allows the user to specifically measure global […]
EpiSeeker Histone H3 (methyl K27) Assay Kit
Product Overview: Methylation of histone H3 at lysine 27 (K27) is a mark of gene inactivation and it is thought to mediate heterochromatin formation by forming a binding site for Polycomb. H3 (methyl K27) is also thought to have an important role in the repression of HOX genes during development and in X chromosome inactivation […]
EpiSeeker Histone H3 (tri methyl K27) Assay Kit
Product Overview: Methylation of histone H3 at lysine 27 has an important role in transcription repression and it is catalyzed by G9a and Polycomb Groups enzymes such as EZH2. In particular, try-methylation of histone H3 at lysine 27 (H3(try methyl K27)) is a facultative heterochromatin mark, which promotes the recruitment of polycomb group proteins for […]