Product Overview: Methylation of histone H3 at lysine 4 by Methyl transferases such as SET1, SET7/9, MLL and Trx among others occurs in mammals in several distinct genomic distributions. Enrichment of H3 (tri-methyl K4) is found at transcription start sites of active genes where they contribute to transcriptional initiation. EpiSeeker Histone H3 (tri-methyl K4) Quantification […]
- Histone Methylation Kits and Assays
EpiSeeker Histone H3 (pan-methyl K4) Quantification Kit (Colorimetric)
Product Overview: Methylation of histone H3 at lysine 4 by Methyl transferases such as SET1, SET7/9, MLL and Trx among others occurs in mammals in several distinct genomic distributions. In mammals, H3(mono-methyl K4) is associated with silenced euchromatin regions whereas H3(di-methyl K4) and H3(tri-methyl K4) is associated with transcriptionally active euchromatin regions. EpiSeeker Histone H3 […]
EpiSeeker Histone H3 (tri methyl K27) Assay Kit (In Situ)
Product Overview: Methylation of histone H3 at lysine 27 has an important role in transcription repression and it is catalyzed by G9a and Polycomb Groups enzymes such as EZH2. In particular, try-methylation of histone H3 (H3(try methyl K27)) is a facultative heterochromatin mark, which promotes the recruitment of polycomb group proteins for gene silencing. Increased […]
EpiSeeker Histone H3 (mono-methyl K9) Quantification Kit (Colorimetric)
Product Overview:Methylation of histone H3 at lysine 9 by ESET, G9a aming other methyl transferases mediates heterochromatin formation by forming a binding site for HP1. H3 (mono-methyl K9) is enriched in certain euchromatin domains which have been postulated to be transcriptionally silent. EpiSeeker Histone H3 (mono-methyl K9) Quantification Kit (Colorimetric) (ab115060) allows the user to […]
EpiSeeker Histone H3 (mono-methyl K9) Quantification Kit (Fluorometric)
Product Overview: Methylation of histone H3 at lysine 9 by ESET, G9a aming other methyl transferases mediates heterochromatin formation by forming a binding site for HP1. H3 (mono-methyl K9) is enriched in certain euchromatin domains which have been postulated to be transcriptionally silent. EpiSeeker Histone H3 (mono-methyl K9) Quantification Kit (Fluorometric) (ab115061) allows the user […]