Active Motif’s Global 5-hmC Quantification Kit is an ELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types (e.g. normal and diseased), treatment conditions, clinical outcomes or environmental backgrounds. The Global 5-hmC Quantification Kit enables higher throughput processing of samples, requires only nanogram amounts of genomic DNA per […]
- Global DNA Methylation Detection
Global DNA Methylation Assay – LINE-1
Global DNA Methylation Assay to quantify genome-wide 5-mC levels in human DNA Simple ELISA assay in a flexible strip-well microplate format Detects as low as 0.5% methylation Detects methylation from as little as 10 ng DNA/well LINE-1 probe used for DNA capture for better specificity Biologically relevant standards provided for improved quantification Active Motif’s Global […]
NOMe-Seq Kit
NOMe-Seq is a first of its kind kit to simultaneously analyze nucleosome occupancy and CpG methylation status on the same DNA strand. NOMe-Seq (Nucleosome Occupancy and Methylome sequencing) is a published method that was developed by the Peter Jones lab at USC and has been validated for gene-specific analysis using both traditional cloning and Sanger […]
5-mC DNA ELISA Kit
The ability to efficiently detect and quantify DNA methylation (i.e., 5-methylcytosine) has become essential for epigenetic-based research. To date, a number of methods have been developed for this purpose including high-performance capillary electrophoresis, bisulfite sequencing, and methylated DNA immunoprecipitation. The 5-mC DNA ELISA Kit is a convenient and powerful tool that allows the researcher to […]
EpiSeeker methylated DNA Quantification Kit (Colorimetric)
Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has […]