Dnmt1 methylates cytosine residues in hemimethylated DNA at 5’…CG…3′. Mammalian Dnmt1 is believed to be involved in carcinogenesis, embryonic development and several other biological functions. The b4k of the methylation takes place during DNA replication in the S-phase of the cell.
- DNA Methyltransferase Enzymes and Assays
HpaII Methyltransferase
HpaII Methyltransferase recognizes the same sequence as the MspI Methyltransferase, but modifies the internal cytosine residue (C5) of the sequence CCGG.
HpaII Methyltransferase
HpaII Methyltransferase recognizes the same sequence as the MspI Methyltransferase, but modifies the internal cytosine residue (C5) of the sequence CCGG.
GpC Methyltransferase (M.CviPI)
The GC Methyltransferase, M.CviPI, methylates all cytosine residues (C5) within the double-stranded dinucleotide recognition sequence 5´…GC…3´.
GpC Methyltransferase (M.CviPI)
The GC Methyltransferase, M.CviPI, methylates all cytosine residues (C5) within the double-stranded dinucleotide recognition sequence 5´…GC…3´.