Product Overview: DNA methylation plays an essential role in biological processess through repression of transcription, while DNA demethylation is necessary, on the other hand, for epigenetic reprogramming of these genes. Active demethylation of DNA requires specific demethylase participation such as from MBD2. EpiSeeker DNA demethylase (total) Activity Quantification Assay Kit (ab113472) allows the user to […]
- Abcam
EpiSeeker MBD2 Binding Activity Quantification Assay Kit
Product Overview: MBD2 (methyl-CpG binding domain protein 2) belongs to a family of MBD domain containing proteins. This family of proteins associates with heterochromatin by their interaction with methylated DNA at CpG islands, and appear to ‘read’ and ‘translate’ the DNA methylation signal into transcriptional repression by recruiting silencing complexes and histone deacetylases among other […]
EpiSeeker Nuclear Extraction Kit
Product Overview: EpiSeeker Nuclear Extraction Kit (ab113474) provides a simple and selective method along with all necessary reagents for extracting nuclear proteins in just 1 hour for a variety of applications such as western blotting, protein-DNA binding assays, nuclear enzyme assays or any other procedures requiring optimized nuclear proteins. The protocol is fast and easy-to-use, […]
EpiSeeker Whole Cell Extraction Kit
Product Overview: EpiSeeker Whole Cell Extraction Kit (ab113475) provides a simple and selective method for extracting whole cell proteins in just 45 minutes for a variety of applications such as western blotting, cellular enzyme assays, or any other procedures requiring cellular proteins. ab113475 can be used to extract cellular proteins from mammalian cells and tissue […]
EpiSeeker Histone Extraction Kit
Product Overview: EpiSeeker Histone Extraction Kit (ab113476) provides a simple and selective method for extracting histone proteins in just 1 hour for a variety of applications such as histone modification such as acetylation, methylation, and sumoylation. ab113476 can be used to extract histones from as low as 105 cells or 1 mg of tissue.