Use the EpiXploreTM Methyl Detection Kit to determine the methylation status of any cytosine residue, directly from genomic DNA. This kit provides excellent retention and yield of bisulfite-modified DNA, and high-quality epigenetic data.
Can Your Current Bisulfite Conversion Kit Compete?
Does your methyl detection kit… | EpiXplore Protocol | Traditional Protocols |
Preserve starting DNA? | Yes. Virtually complete retention of your starting DNA | No. Lose 84–96% of your starting DNA |
Require DNA pretreatment? | No. Works directly on genomic DNA | Yes. You must pretreat with restriction endonucleases |
Work on small samples? | Yes. Start with as little as 50 pg genomic DNA (8 mammalian cells). | No. High degree of loss means you must start with a larger sample |
Applications: Understanding the roles of DNA methylation in embryonic development, gene regulation, chromatin integrity, genomic imprinting, and human diseases including cancer.
View EpiXplore™ Methyl Detection Kit on Clontech’s website