SureSelectXT Human Methyl-Seq is the first comprehensive target enrichment system to enable researchers to focus on the regions where methylation is known to impact gene regulation: CpG islands, CpG island shores, undermethylated regions, promoters, and differentially methylated regions (DMRs).
SureSelectXT Human Methyl-Seq
- Uniquely delivers more information than methylation microarrays by detecting individual CpGs
- Increases throughput and reduces costs compared to whole genome bisulfite sequencing
- Reveals methylated regions not detected by restriction enzyme and immunoprecipitation or SNP-based assays
SureSelect XT Human Methyl-Seq Content Types
- CpG islands
- GENCODE promoters
- Cancer, tissue-specific DMRs, or regulatory features in:
- CpG Islands, shores/shelves (± 4kb)
- Enhancers
- Ensemble regulatory regions
- DNase I hypersensitive sites