SureSelectXT Human Methyl-Seq

SureSelectXT Human Methyl-Seq is the first comprehensive target enrichment system to enable researchers to focus on the regions where methylation is known to impact gene regulation: CpG islands, CpG island shores, undermethylated regions, promoters, and differentially methylated regions (DMRs). SureSelectXT Human Methyl-Seq

  • Uniquely delivers more information than methylation microarrays by detecting individual CpGs
  • Increases throughput and reduces costs compared to whole genome bisulfite sequencing
  • Reveals methylated regions not detected by restriction enzyme and immunoprecipitation or SNP-based assays
SureSelect XT Human Methyl-Seq Content Types
  • CpG islands
  • GENCODE promoters
  • Cancer, tissue-specific DMRs, or regulatory features in:
    • CpG Islands, shores/shelves (± 4kb)
    • Enhancers
    • Ensemble regulatory regions
    • DNase I hypersensitive sites