Move Over Caloric Restriction – Hungry-Hungry Histones Slow Aging!May 30, 2023Kick the kebab, bin the burger, axe the avocado toast?! While caloric restriction represents a hunger-inducing yet effective means to extend lifespans, a tasty new study highlights how “hungry-hungry histones” create a neural hunger “state” that slows aging (even when getting our fill), suggesting that growing old may be more delicious than we think! While […]
Tissue Regeneration Rejuvenates Chromatin Age-Domains to Wake Cells from Hyper-quiescenceMay 22, 2023Taking a break from the hectic world now and again might just save your sanity; however, we sometimes need a push to get back up the pace of everyday life! Now, exciting new tissue rejuvenation-based research into the chromatin age-domains associated with hyper-quiescence suggests that aging cells also suffer from this pesky problem. Aging tissues […]
eBook: Epigenetics of Cancer & Disease RiskMay 3, 2023The application of epigenetic approaches to disease research is moving quickly and hundreds of new papers are published every year, from virology to neurobiology and cancer. In this eBook, we present short summaries of interesting discoveries that caught our attention in each of these areas. Table of Contents Chapter 1: Epigenetics in Disease Risk Taking […]
mRNA Shows Its Age and Quiets Down the Immune System with Cap2 MethylationFebruary 14, 2023Wrinkles, gray hair, … Cap2 methylation on mRNA? It turns out that these are all signs of aging. Two elegant new methods to show that Cap1 gets slowly modified to Cap2 as mRNAs age. And just like boomers, they want to live the quiet life, calming down the innate immune system to prevent autoimmunity. Although […]
You Aren’t Going Crazy – Losing It at the Epigenetic Level Really Drives Aging!February 6, 2023Information loss can drive us crazy – from ruining a potential culinary masterpiece to turning a Lego-building afternoon into a nightmare, but can “losing it” at the epigenetic level drive aging and turn a young whippersnapper into an old fogey? We know all too well about age-related epigenetic changes, and now a team led by […]