Pregnancy Epigenetically Ages Mothers – But Breastfeeding May Reverse ItApril 22, 2024Our mothers might be onto something when they jokingly blame us for their gray hair and wrinkles. In two recent studies, DNA methylation-based epigenetic clocks show that pregnancy, with its far-ranging emotional and physical changes, increases the biological ages of mothers. On the bright side, the effects were reversible in those who breastfed, according to […]
Updated cfDNA Nucleosomics Technology Upgrades our Epigenetic ClocksMarch 4, 2024A new style, novel functionalities, and a better overall product; we always want our smartwatches to employ the latest technology, and why not?! Now, a well-timed update involving cell-free DNA (cfDNA) nucleosomics-based technology provides for a significantly upgraded epigenetic clock, which may boost aging-based research. A punctual team led by Vladimir B. Teif (University of […]
TIME-Seq Flies When Constructing Cost-Effective Epigenetic ClocksFebruary 19, 2024If time drags and money disappears when looking at DNA methylation-based epigenetic clocks, you are “in time” to hear of a newly described efficient and cost-effective bisulfite sequencing approach! Time flies – but money does not – with “tagmentation-based indexing for methylation sequencing” or TIME-seq! An on-time team led by David A. Sinclair (Harvard Medical […]
An Evolutionary and Epigenetic Tour-de-force Links DNA Methylation and Mammalian AgingSeptember 11, 2023Have you climbed Mount Everest? Recorded a critically acclaimed album?? Written the great American novel??? These life-affirming feats of body and mind pale into insignificance when compared to the evolutionary and epigenetic tour-de-force reported in two recent papers based on mammalian DNA methylation datasets of colossal size and importance. An expeditionary force led by Steve […]
Bringing in “Young Blood” Persistently and Systemically Slows Epigenetic AgingAugust 22, 2023Be it a football team, a book club, or an epigenetics lab, bringing in “young blood” can seriously improve quality in the short term, but does this effect endure? Now, a heterochronic parabiosis study reveals that long-term exposure to young blood induces persistent slowing of DNA methylation-based epigenetic aging and extends healthy lifespans in mice! […]
