Free Conference Registration for Upcoming ConferencesAugust 7, 2016Fall in San Diego means great weather, uncrowded beaches, and lovely surf, which means we’re not leaving. That’s good news for you though as we’re sending our community members to cover these great upcoming conferences. Please have a look at each of these and respond using the form at the footer of this post if […]
Colon Organoid Model: A New Tool for Cancer ResearchJuly 23, 2016The English sea captain and politician Sir Francis Drake believed in “sic parvis magna”, or “greatness from small beginnings”. While he hasn’t been around to see the recent explosion in organoid (or mini-organ) research, we are sure he would be impressed. Measuring a few millimeters in diameter and produced via three-dimensional differentiation of stem cells, […]
R-Loops at Gene Promoters and Terminals Mark the EpigenomeJuly 18, 2016In today’s loopy world, the wise words “Those who cannot remember the past are condemned to repeat it” have a particular resonance. Thankfully, our epigenomes are dynamic historians that get the message and make use of past transcripts by forming R-loops. R-Loops and the Epigenome R-loops are RNA-DNA hybrids: a 3 stranded nucleic acid structure. […]
Extra-Coding RNAs (ecRNAs) Sculpt Dynamic DNA Methylation of the BrainJuly 18, 2016We’ve got our mind on methylation and methylation in our mind, but we are often left wondering how DNA methylation got there in the first place. Well, that cognitive tongue twister has now been cracked by a class of RNA that likes to interact with DNA methyltransferases. Extra coding RNAs (ecRNAs) originate from the sense […]
Hey Methylation, Thanks for the MemoriesJuly 18, 2016Memories; we all have some we would rather forget, and some that we will hold onto forever. But how exactly is memory formed and what are the biochemical pathways that are in play? Recent studies have indicated that RNA and DNA adenosine methylation are important for the conversion of experiences, both good and bad, into […]