Webinar: Using CRISPR/Cas9 Technology for Editing Genes in Haematopoietic Cells and MiceJuly 29, 2014Presented by: Dr Marco Herold, Laboratory Head, Molecular Genetics of Cancer Division, The Walter & Eliza Hall Institute of Medical Research Abstract: The CRISPR/Cas9 technology provides an easy and rapid way to edit genes in vitro and in vivo. Initial experimental strategies utilized a transient transfection approach to modulate genes in vitro, but this proved […]
TAL Effectors Dig the Long Distance ThingJuly 25, 2014If you think the subway is crowded you haven’t seen what a TAL Effector (TALE) has to put up with when getting to work. In a new study involving the production of more than 200 TALE modulators, researches at Beijing University found the long sought explanation of why some TALEs effectively modulate transcription while others do not. […]
CRISPRs and TALENs Stay on Target in Stem Cell GenomesJuly 25, 2014Some of our most touted advancements in weaponry involve ‘surgical strike capabilities’, the idea being that the more precisely you attack a specific target, the less unintended damage there will be. Recent innovations in genome editing, such as CRISPRs and TALENs, may provide researchers with an improved genomic targeting system, enabling more precise aiming towards […]
Blame Your Old Man: Age-Related Sperm Methylation Changes May Up Disease OddsJuly 24, 2014Delayed parenthood in developed countries means more old dads.  Who cares you ask? You should, as this trend doesn’t just increase early morning traffic at Starbucks, it can also increase the incidence of autism, bipolar disorders, schizophrenia, some forms of cancer, or other disorders that accompany the offspring of older fathers. Way to go Dad; […]
Webinar – Bringing ChIP Seq Data into Focus: Advanced Normalization StrategiesJuly 23, 2014If you’ve ever struggled to make sense of your ChIP Seq data, then check out this webinar presented by our colleagues at Active Motif, to get some ideas on how to bring some order to the chaos of ChIP-seq. Presented by Brian Egan, Ph.D, Epigenetic Services Manager at Active Motif Normalization of ChIP-seq Data Today, […]