Whether you are performing drug discovery screening, analyzing enzyme kinetics or monitoring changes in histone modifications, substrate selection is critical. Nucleosomes offer the advantage of providing a more biologically relevant substrate when compared to histone proteins alone or synthetic peptides. To best mimic cellular biology with your in vitro assay, use Active Motif’s Recombinant Nucleosomes. […]
- Histone Peptide Arrays
AbSurance™ Complete Core Histone Antibody Specificity Array
The AbSurance Complete Core Histone Antibody Specificity Array is comprised of 89 high quality modified and unmodified histone peptides ( >95 % purity) spotted on Immobilon® P PVDF membranes in a 96-well format. One membrane contains 46 histone H3 peptides (8 acetylated, 27 methylated, 5 phosphorylated, and 6 unmodified). The other membrane contains 43 histone […]
MODified™ Histone Peptide Arrays
Active Motif’s new MODified™ Histone Peptide Arrays (Catalog Nos. 13001 & 13005) provide researchers with a valuable tool to screen antibodies, enzymes and proteins for cross-reactivity or binding interactions with histones and their post-translational modifications. The MODified Histone Peptide Arrays screen 59 acetylation, methylation, phosphorylation and citrullination modifications on the N-terminal tails of histones H2A, […]