Active Motif’s MethylCollector™ Ultra offers a fast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA. MethylCollector Ultra is based on the Methylated CpG Island Recovery Assay (MIRA) which uses a MBD2b/MBD3L1 protein complex for improved enrichment of CpG dinucleotides. Enriched DNA can be used in many downstream applications, such as […]
- DNA Methylation Enrichment Kits
EpiSeeker methylated DNA Immunoprecipitation (MeDIP) Kit – DNA
Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position of a CpG dinucleotide which leads to epigenetic inactivation of genes when found in 5′-CpG-3’dinucleotides within promoters or in the first exon of genes. It has been demonstrated that DNA methylation plays an important role in the regulation of […]
EpiSeeker methylated DNA Immunoprecipitation (MeDIP) ChIP Kit
Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position of a CpG dinucleotide which leads to epigenetic inactivation of genes when found in 5′-CpG-3’dinucleotides within promoters or in the first exon of genes. It has been demonstrated that DNA methylation plays an important role in the regulation of […]
EpiSeeker methylated DNA Immunoprecipitation (MeDIP) Kit – Tissue
Product Overview: DNA methylation is a covalent modification of the cytosine ring at the 5′ position of a CpG dinucleotide which leads to epigenetic inactivation of genes when found in 5′-CpG-3’dinucleotides within promoters or in the first exon of genes. It has been demonstrated that DNA methylation plays an important role in the regulation of […]
EpiSeeker MBD2 ChIP kit
Product overview: MBD2 (methyl-CpG binding domain protein 2) belongs to a family of MBD domain containing proteins. This family of proteins associates with heterochromatin by their interaction with methylated DNA at CpG islands, and appear to ‘read’ and ‘translate’ the DNA methylation signal into transcriptional repression by recruiting silencing complexes and histone deacetylases among other […]