miRNome MicroRNA Profilers Genome-wide qPCR microRNA expression profiling These MicroRNA qPCR Array Panels come with all the reagents necessary to tag and convert small RNAs from 20 different total RNA samples into quantifiable cDNA using the sensitive QuantiMir technology. The kits include assays in pre-formatted plates for either the full compliment of human, mouse or […]
- System Biosciences
miR and PIWI-SNaREs
miR-SNaREs and PIWI-SNaREs – Small Non-coding RNA Enrichment Overexpress Epitope tagged microRNA processing factors and PIWI factors for IP pull-downs of RNAs and associated protein complexes. Lentivector based expression of DGCR8 (Pasha), DICER and AGO2 (Argonaute) for miR-SNaREs and PIWIL-1,-2,-3 and -4 for PIWI-SNaREs. All constructs contain N-terminal HA tags for simple immunoprecipitation experiments. Constructs available […]
MicroRNA Target Selection System
The miR-Selection lentivector features a dual reporter system with firefly luciferase (Fire) and a cytotoxic sensor (Ctx). The miR-Selection platform captures the 3’ UTR to microRNA binding event using a survival screen by modulating the reduction of the cytotoxic sensor. Quantitative validation is made simple using the built-in luciferase reporter. This powerful and elegant technology […]
Lenti-miR™ MicroRNA Precursor Clone Collection
The most comprehensive microRNA Precursor Clone Collection in HIV-based Lentiviral Vectors available anywhere. There are expected to be over 1,000 microRNAs encoded in the human genome and they function by either blocking translation of, or degrading, mRNA species corresponding to specific genes. While the number of verified human microRNAs is expanding, there is an increasing […]
miRZips™ Lentiviral-based MiRNA Inhibition
miRZip anti-sense microRNAs are stably expressed RNAi hairpins that have anti-microRNA activity. These miRZip shRNAs produce short, single-stranded anti-microRNAs that competitively bind their endogenous microRNA target and inhibit its function. The result is the derepression and elevation of the protein levels of the transcripts targeted by the microRNA being “zipped”. The miRZip short hairpin RNAs are […]