The combination of ChIP with genome-wide analysis using Next-Generation sequencing (ChIP-Seq) is a powerful approach that can provide insights into gene regulation by identifying global binding sites for proteins of interest. Active Motif’s ChIP-IT® ChIP-Seq Kit provides proven reagents, streamlined protocols and validation controls to give you confidence in successful ChIP-Seq using the Illumina®sequencing platforms. The […]
- All Products
EZ Nucleosomal DNA Prep Kit
The EZ Nucleosomal DNA Prep Kit is a streamlined procedure for the isolation of nucleosome-associated DNA. The kit includes reagents/procedures for: cell nuclei isolation, intact nuclei enzymatic digestion, and nucleosomal DNA purification. This kit includes two different enzymes for nucleosomal DNA preparation: Atlantis dsDNase and micrococcal nuclease. Atlantis dsDNase is a double-strand DNA specific endonuclease […]
SureSelectXT Human Methyl-Seq
SureSelectXT Human Methyl-Seq is the first comprehensive target enrichment system to enable researchers to focus on the regions where methylation is known to impact gene regulation: CpG islands, CpG island shores, undermethylated regions, promoters, and differentially methylated regions (DMRs). SureSelectXT Human Methyl-Seq Uniquely delivers more information than methylation microarrays by detecting individual CpGs Increases throughput […]
ChIP-IT® High Sensitivity
The ChIP-IT® High Sensitivity (HS) Kit is designed to give superior performance when using antibodies against low abundance transcription factors, antibodies with sub-optimal binding affinities or when starting with a limited number of cells. Higher signal and lower non-specific DNA pulldown is achieved through the incorporation of specialized protein G agarose beads and optimized fixation, […]
NOMe-Seq Kit
NOMe-Seq is a first of its kind kit to simultaneously analyze nucleosome occupancy and CpG methylation status on the same DNA strand. NOMe-Seq (Nucleosome Occupancy and Methylome sequencing) is a published method that was developed by the Peter Jones lab at USC and has been validated for gene-specific analysis using both traditional cloning and Sanger […]