Fire Up Your Methylation Analysis With QIAGEN’s PyroMark CpG AssaysApril 26, 2011Fast, inexpensive, and accurate, pyrosequencing has become a go-to method for many researchers looking for quantitative methylation data. Designing methylation assays using primers for bisulfite converted DNA can be tricky though, and dealing with assay optimization is no small feat either. Fortunately those worries go up in smoke with QIAGEN’s new PyroMark CpG Assays. Custom […]
OneStep For DNAm qPCR, One Giant Leap For DNAm AnalysisApril 19, 2011In the past, the route to locus-specific methylation detection resembled more of a brutal molecular biology pentathlon than a microfuge tube. If you’re into that kind of abuse, that’s cool, but you probably won’t be interested in Zymo’s new OneStep qMethyl™ Kit. This slick system closes the lid on the old school tool set and […]
Pull Down a Winner with Abcam Antibody PanelsMarch 29, 2011It’s a big step. It’s stressful. Deciding which antibody will be “the one” in your ChIP applications isn’t easy, but you can relax a bit now as our good friends at Abcam must have sensed a touch of that antibody commitment-phobia within the research ranks, as they’ve just launched Abcam Antibody Panels; a way to let […]
Combo Your 5-hmC and 5-mC Detection with NEB’s EpiMark™ 5-hmC KitMarch 14, 2011If locus-specific DNA methylation is your game, then you already know that 5-hmC is something that you just can’t ignore. But setting up a round of experiments to figure out the 6th base’s role in your samples is no walk in the park, either. Happily, New England Biolabs has solved that quandary for you with […]
Going Big in Small Samples with the Magna ChIP-Seq™ KitMarch 1, 2011It used to be that smaller, data-rich samples lived peacefully below the threshold of utility where they were safe from the scientific ambitions of researchers. Not anymore. Recent innovations have really come together in products like Millipore’s Magna ChIP-Seq™ Chromatin Immunoprecipitation and Next Generation Sequencing Library Preparation Kit, that have small samples scrambling for cover. How […]
Wanted: Genome-Wide DNA Methylation Data, No Experience RequiredFebruary 15, 2011Until recently, it’s been mostly the epigenetics gurus dominating genome-wide methylation analysis publications. It makes sense, big labs means big resources. Lucky for you, those days have passed. You are now free and clear to boost your status to the next level with genome-wide methylation data and you don’t have to be an expert to […]
ChIP-Seq Libraries Made Easy with NEBNext® ReagentsFebruary 1, 2011A wealth of answers exist within the world’s libraries. Shouldn’t the same be true for your ChIP-Seq library? Sequencing has catapulted the output of ChIP analyses to levels most researchers wouldn’t have dreamed of just a few short years ago, but the quality of all of that output depends on a number of factors, including […]
ChIP in a Box: Success with Abcam’s ChIP Kit and Primer SetsJanuary 19, 2011Sometimes thinking inside the box isn’t such a bad thing. Especially if that box contains the key ingredients to successful ChIP experiments like Abcam’s ChIP Kit. Abcam may be more known for its diverse antibody collection, but they also make kits to make those antibodies hum in applications like ChIP. Abcam’s ChIP Kit contains most of […]
CpGenome™ Turbo Bisulfite Modification Kit: The Fastest Route from C to UDecember 2, 2010You don’t always need to take shortcuts to get where you need to be faster. Thanks to the CpGenome™ Turbo Bisulfite Modification Kit from Millipore, now you can get from C to U with your bisulfite conversion reactions faster than ever. Just think of what you’ll do with that extra time you’ll save. Bisufite Conversion […]
Zymo’s Quest 5-hmC Detection Kit Covers All the BasesNovember 10, 2010If you’re kicking off an expedition to explore the great hydroxymethylated unknown, make sure you’re geared up with the right equipment. Until recently, 5-hmC detection methods could only give you a general idea of the hydroxymethylation profile of your sample, but the new Quest 5-hmC Detection Kit™ let’s you see exactly where those 5-hmC marks […]
