Get Captivating Performance with Zymo’s Genome-wide 5-hmC Analysis ServiceNovember 29, 2011The interest in 5-hydroxymethylcytosine (5-hmC) seems to be increasing faster than the national debt, but there still aren’t many tools available to aid scientists in understanding the 6th base, especially in a genome-wide context. Most current antibody and IP-based approaches are useful but can be a little difficult when applied to NGS. Fortunately, the methylation […]
SIRTainty™ is Key to Trustworthy HDAC DetectionOctober 26, 2011There aren’t too many things that you can be sure about these days, but if you’re studying class III HDACs, aka sirtuins, then getting a little SIRTainty™ is now as easy as ordering a kit. The SIRTainty™ Class III HDAC Assay is a new assay, with novel patent pending technology, designed to measure sirtuin activity […]
Zymo OneStep qMethyl™ Arrays Fill Your Plate with DNA Methylation Screens.September 29, 2011OneStep qMethyl™ Kits enable easy, bisulfite-free DNA methylation analysis of a particular locus by combining Methylation Sensitive Restriction Enzyme digestion and real-time quantitative PCR into one step. Now the methylation masters at Zymo Research have added even more flavor to the qMethyl™ entrée with the launch of OneStep qMethyl™ Arrays, pre-designed assays for select targets served […]
Tap into Tissues with Millipore’s Magna ChIP™ G Tissue KitSeptember 1, 2011Henrietta Lacks and Chinese hamster ovaries have all spawned cell lines that are cornerstones of biological research, but sometimes the chromatin immunoprecipitation (ChIP) answers you’re looking for can’t be found in the flasks of cultured cells. Studying chromatin and histone modifications in animal materials provides a snapshot of the actual, region specific, physiological conditions of […]
RNA On-Demand: Direct–zol™ From Zymo ResearchAugust 17, 2011The boom in RNA research has made the need for quality RNA samples climb faster than the price of gasoline. Unfortunately, RNA isolation techniques haven’t matched that trend, forcing researchers to spend hours on laborious methods to get the amount and quality of RNA they’re looking for. So, not only is top-notch RNA in demand, […]
Genome-Wide and High-Resolution Methylation Profiling Together at LastJuly 15, 2011What do you get when you pair up bisulfite conversion with custom SureSelect™ DNA Capture Arrays? Answers of course, in the form of site-specific methylation data for tens of thousands of CpG sites. For years, adjectives like “high-resolution” and “genome-wide” have been on the wish list of epigenetics researchers keen on tackling the complexities of DNA […]
Automated Epigenetics: Diagenode’s SX-8G IP-Star Compact SystemJuly 6, 2011After slaving away all day at the bench just to run a handful of epigenetic assays, you’ve probably wished that there were some sort of robot around that could do most of the work for you. Now, Diagenode’s SX-8G IP-Star Compact Automation System turns that fantasy into a reality. The IP-Star Compact instrument harnesses the […]
Become a Methyl-Detective Using QIAGEN’s EpiTect Plus Bisulfite KitsMay 19, 2011Bisulfite conversion is still the gold-standard method used to investigate DNA methylation, but that doesn’t mean it’s easy. When you’re trying to solve the mystery of methylation in your favorite samples, you want tools that will get you to the right answer, right away. QIAGEN’s EpiTect Plus Bisulfite Kits takes you all the way from […]
Doubling Down on 5-hmC Profiling with Dual MeDIP from DiagenodeMay 11, 2011A year after 5-hydroxymethylcytosine’s (5-hmC) dramatic entrance into the epigenetics research scene, the research community has a long list of questions to ask about the 6th base. Investigations into 5-hmC were sidelined for most of the year due to the absence of methods to analyze it. Thankfully those helpless days are history as Diagenode just […]
Enrich Your DNA Methylation Experience with NEB’s EpiMark™ KitMay 4, 2011Do you dread launching your next DNA methylation study with the same old affinity reagents? Worried that it’ll take too much time, or that the specificity just won’t hack it? Then fret no more, because the latest EpiMark™ DNA Methylation Enrichment Kit from New England Biolabs is here to offer a much more fulfilling experience. […]
