Go Into the Light With Promega HDAC-Glo™ 2/IIa AssaysFebruary 18, 2014Searching for that next great HDAC inhibitor can be a grueling task, but now the R&D team at Promega has just introduced the HDAC-Glo™ 2 and IIa Assays to make your HDAC screening life a whole lot better. Just like the rest of the HDAC-Glo™ Assay family, the HDAC-Glo™ Class IIa and HDAC-Glo™ 2 Assays […]
Zymo-Spin™ ChIP Kits Give Chromatin Immunoprecipitations the Run-aroundFebruary 5, 2014After an extensive development and beta-testing process, the innovators at Zymo Research have unveiled the new Zymo-Spin™ ChIP Kit, which provides a whole new twist to standard chromatin precipitations. Special Discount to EpiGenie Readers: Get 20% OFF and a free “Blame It On My Epigenetics” T-shirt with every purchase of Zymo-Spin™ ChIP Kit (Catalog No. […]
Promega SIRT-Glo™ Assays Illuminate the Search for SirtuinsDecember 11, 2013Sirtuins (SIRTs) sure seem to getting around. These energetic class III HDAC enzymes have their fingerprints on everything from Alzheimer’s to Inflammation, generating enough spotlight (and even a little controversy) to make even Kanye West a feel little jealous. Promega’s new SIRT-Glo™ Assays and Screening Systems are the latest tool to help researchers study the […]
Zymo ChIP DNA Clean & Concentrator™: A New Twist on Chromatin ImmunoprecipitationSeptember 10, 2013If you’re one of those researchers who has been avoiding ChIP experiments like the plague because of the aggravating low yields and poor quality ChIP DNA associated with traditional ChIP protocols, then it’s time to give the ChIP DNA Clean & Concentrator™ (ChIP DCC™) Kit from Zymo Research a whirl. The ChIP DCC™ is a […]
Purity By Design – Zymo Research Cleans Up DNA for Epigenetic AnalysisAugust 6, 2013Question the design of your spin column. All spin columns are not created equal, and designs from some other companies may result in buffer retention, even after centrifugation. The buffer carry-over can contain high concentrations of salts, detergents, and other buffer components that are eventually eluted from the column along with your DNA or RNA […]
How Active are Your HDACs? Abcam HDAC & SIRT Activity Assay KitsJuly 25, 2013Based on their booming popularity lately, it seems that histone deacetylases (HDACs) and sirtuins (SIRTs) lead pretty active epigenetic lives. As the experiments continue, there are several reasons why the epigenetics research community would want to keep tabs on what HDACs and SIRTs are doing including: Assessing HDAC or SIRT purification Screening for HDAC/SIRT inhibitors […]
A Great Start to RNA-Seq: Zymo Research’s RNA Clean & Concentrator™-5July 1, 2013With every high-tech advance in the methods used for RNA analysis , the need for extremely pure RNA input samples becomes even more crucial. The RNA Clean & Concentrator™-5 (RCC™-5) Kit from Zymo Research packs high-performance into a fast and easy format that enables even the most demanding methods, including RNA-Seq. RNA Clean and Concentrator™-5 […]
HDAC-Glo™ Brightens up HDAC Activity ScreeningJune 21, 2013Histone Deactylase (HDAC) researchers have been clamoring for more sensitive and reliable HDAC assays in order to generate the high quality data that previous techniques don’t always deliver. The HDAC-Glo™ I/II Assays and Screening Systems from Promega aim to shine new light on the matter with highly sensitive assays that ditch the old, troublesome false […]
MethylEdge™: Bisulfite Conversion without FragmentationMarch 27, 2013Bisulfite conversion kits for DNA methylation studies are notorious for causing high levels of sample DNA fragmentation. What a pain. You may as well be flushing a portion of your hard-won samples down the sink. And the only way around it is to start off with more sample in the first place, which seriously limits […]
Go Small with EpiSeeker Bisulfite Modification Kit – Whole CellFebruary 14, 2013In DNA methylation studies, some of the biggest findings come in the smallest sample sizes. But if you’re not using the right bisulfite conversion system, potential gold in samples like tissue biopsies, microdissected samples, and stem cells might be off limits. That is of course, unless you’re using a slick system like Abcam’s Bisulfite Modification […]
