Get Tissue-Specific with EMD Millipore’s CpGenome™ 5-hmC Quantitation KitDecember 26, 2012One of the few things epigenetics researchers know for sure about 5-hmC, is that it’s highly variable amongst different types of tissues and cell types. So where does your favorite sample fall on the 5-hmC quantity spectrum? Thanks to the new CpGenomeTM 5-hmC Quantitation Kit from EMD Millipore that question is easier than ever to […]
One Step ChIP with Abcam’s EpiSeeker ChIP KitNovember 20, 2012Antibody companies like Abcam run a ton of ChIP experiments, so they’re all too familiar with the amount of variability that can lurk in every step of the ChIP protocol. So what’s the safest way to reduce variability and get consistent results? Reduce the steps of course; and that’s exactly what the EpiSeeker ChIP Kit […]
EMD Millipore AbSurance™ Histone Peptide Arrays: Insurance for Your AntibodiesJune 23, 2012It’s never a bad idea to insure the important things in life against disaster. Wouldn’t it be great if epigenetics researchers could do the same for an upcoming experiment? Although they aren’t exactly in the insurance game, EMD Millipore has designed the new AbSurance™ Histone Antibody Specificity Arrays to act as a protective policy against […]
Bring the Heat to Your Bisulfite Conversion with Zymo’s EZ DNA Methylation-Lightning™ KitsJune 22, 2012A few years ago, researchers performing bisulfite conversion in their DNA methylation studies had a nice break in their bench routine compliments of a 3-hour to overnight incubation during the conversion process. Well we’re sorry to inform you…but Zymo Research just introduced the DNA Methylation-Lightning™ Kit, which takes that incubation down to an hour. Great […]
Abcam EpiSeeker Assays Lead the Search for DNMT KnowledgeJune 13, 2012DNA methyltransferases (DNMTs) have been a trending topic in the epigenetics community for years because of their role in cytosine methylation. Studies that set out to pin down the precise function of DNMTs in various disease and developmental states often introduce more questions than answers. To get to the bottom of DNMT function, you need […]
Covaris AFA: Shear Elegance for ChromatinJune 5, 2012Chromatin shearing is a key step in the ChIP workflow that can dramatically impact your experimental outcome, but so often the task of chromatin shearing is tackled with just brute force. Sub-optimal sonication or enzymatic approaches are like using a sledgehammer to chop fruits and vegetables. Fortunately, Covaris’ Focused-ultrasonicators use Adaptive Focused Acoustics (AFA) technology […]
Active Motif MeDIP-Seq Services Will Put You On the Right MethylPath™April 17, 2012Let’s say you want to get the ball rolling for studies on a new disease. You know you want to search for any important changes in methylation patterns; but with a whole genome worth of ground to cover, how do you decide where to look first? Active Motif now offers the MethylPath™ MeDIP-Seq Service that […]
96 Reasons To Love Millipore’s Magna ChIP™ HT96 KitsApril 4, 2012Chromatin immunoprecipitation (ChIP) is the workhorse of the epigenetics world, like a penny-stock is to a Wall St. broker. So why run just one or two at a time? That’s so five years ago. Now that the EMD Millipore Magna ChIP™ HT96 kits are on the scene, you can churn out up to 96 ChIP […]
ChIP and Discs: Porvair’s Chromatrap® ChIP Kits Break through the NoiseMarch 22, 2012Over the last decade, the ChIP process has seen more enhancements than the Orange County Housewives. Improved antibodies, beads, and fine-tuned buffers—they’ve all ChIP’d in to take this useful method primetime in labs all over the globe. But there’s always room for improvement. Turning Up the Pull Down for Small Sample ChIP Some of the […]
Master Your Bromodomain with Cayman Chemical’s BRD Assay KitsFebruary 10, 2012Bromodomains have had screening groups in their pocket ever since emerging as an attractive drug target. It’s been much easier for researchers to get excited about this class than it has for them to find potent and selective inhibitors of these closely related domains…until now. Cayman Chemical has developed a robust in vitro system for […]
