lncRNAs Give a Shout Out to Imprinted GenesMay 22, 2014For a while there, it didn’t seem like long non-coding RNAS (lncRNAs) had very much to say on the subject of genomic imprinting. But some new evidence shows that lncRNAs have found their voice, shouting loud and clear as a cross-talk conduit between imprinted regions. Researchers from Hebrew University (Jerusalem) introduced a new concept into […]
Non-coding RNAs Reveal How Stress Can Be InheritedMay 7, 2014Stress hits every one of us, like when the Heartbleed virus makes you have to go back and reset all of your online passwords. Recent evidence has already linked the DNA methylation and histone alterations left behind by stressful events to transgenerational epigenetic inheritance, but now, scientists from the Brain Research Institute in Switzerland have observed […]
DNA Cubes May Take Genome Editing Outside the BoxApril 22, 2014Through the use of some creative chemistry researchers have devised DNA cubes that can deliver molecular packages with precision that would make FedEx jealous. A geometrically genius team from McGill University crafted a piece of DNA origami that will only release it’s molecular payload when triggered by a specific mRNA. Here’s how they did it: Cubes were […]
Transgenerational Epigenetic Inheritance TimelineMarch 17, 2014Molecular inheritance is what genetics is all about, so here we highlight some examples where the epigenome plays a key role in inheritance.
EpiGenie Book Reviews: Epigenetics by L. ArmstrongMarch 14, 2014After working on some of the UK’s first embryonic stem cells and developing the world’s first cloned human embryos, Lyle Armstrong turned his attention to the creation of a useful text that would benefit the epigenetic novice as well as the seasoned investigator. With a number of groovy figures and illustrations, they key concepts of […]
Webinar: Genetic Analysis of the Physiological Roles for lncRNAs in DevelopmentMarch 8, 2014Loyal A. Goff, Ph.D presents his research on: Genetic Analysis of the Physiological Roles for lncRNAs in Development Abstract: Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological […]
Great Deals on Insight Pharma’s Epigenetics ReportMarch 5, 2014Our friends at Insight Pharma Reports created an exclusive deal, just for EpiGenie readers: Get 25% off of their new epigenetics report. This is a must have for anyone that needs to stay in tune with the epigenetics research market. There, now don’t you feel special? Epigenetics: Emerging Targets, Available Technologies, Expert Interviews, and an […]
Epigenetics Special Issue: Non-coding RNAs in Epigenetic RegulationFebruary 17, 2014From the very beginning, EpiGenie has held a place in our hearts for non-coding RNAs. That’s why we were stoked to see that the Landes journal Epigenetics dedicated an entire issue to the enigmatic and always interesting little transcripts. The Epigenetics: Special Focus on Non-coding RNAs in Epigenetic Regulation issue features a boatload of reviews […]
SIRT1, miR-34a Clear Out the JNK from Fatty LiversFebruary 11, 2014When it comes to liver disease, it seems most of the attention (and research) goes to the variety that is associated with the consumption of alcohol. While that’s a big concern for those of us enjoy the occasional adult beverage, it’s left non-alcoholic fatty liver disease (NAFLD) under-studied. But now that’s changing. According to Rui […]
Clinical Epigenetics TimelineFebruary 10, 2014The underlying goal for most epigenetic research projects is to eventually lead to a therapeutic clinical application. Here we provide a history of clinical epigenetic advances in this interdisciplinary field as told through our articles and Conference Highlights.