Great Deals on Insight Pharma’s Epigenetics ReportMarch 5, 2014Our friends at Insight Pharma Reports created an exclusive deal, just for EpiGenie readers: Get 25% off of their new epigenetics report. This is a must have for anyone that needs to stay in tune with the epigenetics research market. There, now don’t you feel special? Epigenetics: Emerging Targets, Available Technologies, Expert Interviews, and an […]
Epigenetics Special Issue: Non-coding RNAs in Epigenetic RegulationFebruary 17, 2014From the very beginning, EpiGenie has held a place in our hearts for non-coding RNAs. That’s why we were stoked to see that the Landes journal Epigenetics dedicated an entire issue to the enigmatic and always interesting little transcripts. The Epigenetics: Special Focus on Non-coding RNAs in Epigenetic Regulation issue features a boatload of reviews […]
SIRT1, miR-34a Clear Out the JNK from Fatty LiversFebruary 11, 2014When it comes to liver disease, it seems most of the attention (and research) goes to the variety that is associated with the consumption of alcohol. While that’s a big concern for those of us enjoy the occasional adult beverage, it’s left non-alcoholic fatty liver disease (NAFLD) under-studied. But now that’s changing. According to Rui […]
Clinical Epigenetics TimelineFebruary 10, 2014The underlying goal for most epigenetic research projects is to eventually lead to a therapeutic clinical application. Here we provide a history of clinical epigenetic advances in this interdisciplinary field as told through our articles and Conference Highlights.
Epigenetics of Cancer TimelineFebruary 9, 2014Epigenetic mechanisms have been studied in cancer for decades. Unfortunately, we haven’t been around that long, but check out these great articles that capture the recent history of epigenetic breakthroughs in cancer.
The Rise of lncRNAs TimelineFebruary 9, 2014Long non-coding RNAs, also known as lncRNAs, are gaining a truck load of momentum in the field of the epigenetics. Here we highlight the hottest research, methods papers, and the occasional interview centered around these long and curvy regulatory RNAs.
Evolution of Advanced Sequencing TimelineFebruary 7, 2014In a few short years. advanced sequencing has become nearly ubiquitous. Here we provide a history of how emerging sequencing technologies have driven epigenetic research and understanding.
World’s First CRISPR MonkeysFebruary 5, 2014The Crispr/Cas9 genetic engineering system has gotten a lot of buzz lately for its potential in epigenetic editing and now a team of researchers in China have just made a huge breakthrough, using the technique to create genetically engineered monkeys. The scientists approach was to inject an engineered bacterial immune system (known as CRISPR/Cas9) into one-cell-stage […]
Webinar: Mechanisms of Epigenetic Regulation in Stem Cells and DevelopmentJanuary 31, 2014Dr. Alexander Meissner discusses the roles of epigenetic mechanisms in stem cells and development. Cytosine methylation in mammals is an epigenetic modification that is largely restricted to CpG dinucleotides and serves multiple critical functions including stable repression of target promoters, maintaining genomic integrity, establishing parent-specific imprinting patterns, and silencing endogenous retrotransposon activity. In somatic tissues, […]
The Next Steps in Chromatin Contact Analysis with Dr. Gerd BlobelJanuary 20, 2014Dr. Gerd Blobel discusses emerging techniques for visualizing the interactions of RNAs and chromatin. The Future of Chromatin Contact Analysis So there are other approaches that people are taking, which is: you use FISH, for example, Fluorescent In Situ Hybridization. And this is a method that can be used to validate interactions that have been […]
