Small RNA-mediated Gene ActivationFebruary 25, 2012EpiGenie recently reviewed the epigenetic text RNA and the Regulation of Gene Expression by Kevin Morris. To give you a small taste of the material covered in the book, here is a summary of one of the chapters: Small RNA-mediated Gene Activation by Long-Cheng Li Noncoding RNAs (ncRNA) which, by definition, do not code for […]
The New Human Epigenome Browser from WashUFebruary 23, 2012Looking for the latest in epigenome data analysis tools? Then you’ll want to check out Washington University’s latest creation; The Human Epigenome Browser. Built as part of the Roadmap Epigenomics Project to house and view Human Epigenome Atlas data, this new platform comes with all sorts of slick features to make analyzing, comparing and integrating […]
Cells Socialize via miRNAs to Protect Against AtherosclerosisFebruary 16, 2012Nowadays, there are ton of ways to talk to your friends—phone, text, email, Facebook, Twitter, Skype…Now, an international team of researchers add to the growing literature showing that cells can talk to each other by sending out vesicles with miRNAs in them. This time, the cells are inside blood vessels, and the message is to […]
Epigenetics and TwinsFebruary 8, 2012Every summer outside Cleveland, Ohio identical twins congregate at the Twins Days Festival. Twins from all over join in on an assortment of activities over three days that resembles a massive Doublemint® gum commercial. It’s not just the twins that get stoked for the festival though. As was highlighted in a nice article in National […]
EpiGenie Reviews RNA and the Regulation of Gene ExpressionFebruary 1, 2012The concept of gene regulation by RNAs wasn’t always as well accepted as it is today, and even now some view the idea as controversial. The text RNA and the Regulation of Gene Expression, edited by Kevin Morris, explores the evidence that has convinced many top researchers of the important roles that RNAs have in […]
Microparticles Let miRNAs Cruise the Circulatory Super-HighwayJanuary 23, 2012MicroRNAs have attracted interest as potential blood biomarkers for various cardiovascular diseases, but researchers haven’t quite figured out how they avoid destruction while in the bloodstream. Sort of like tiny outlaws on the run, while traveling the circulatory super-highway miRNAs must nimbly evade the RNAases that might catch them in order to reach their destination […]
Technology & Methods: 2011 Editor’s FavoritesJanuary 11, 2012Without advanced technology, epigenetic research would flounder. (You’d also probably be reading this on a stone tablet, which are really tricky to post on the web.) Check out our favorite improvements in technologies and methods from 2011 that are making sure epigenetic research is staying on the cutting edge. Single Cell Methylation Profiling The Restriction […]
Non-Coding RNA: 2011 Editor’s FavoritesJanuary 11, 2012Understanding of non-coding RNAs grew by leaps and bounds in 2011, but the more that we learn; the more we get the feeling that this is just the tip of the iceberg. Take a look at some of our favorite articles from the last year that highlights the variety of roles that non-coding RNA play. […]
MiRNA Workout Helps Lower HypertensionJanuary 10, 2012Getting the heart pumping with a little exercise is good for the body—it lowers blood pressure and helps fight off heart disease. That makes getting fit a popular New Year’s resolution, but still no one really understands the molecular mechanism that’s behind the scenes. Now, reports show that exercise’s benefits may be due to its […]
Databases for EpigeneticistsDecember 13, 2011The holidays have come a little early for epigeneticists! Nucleic Acids Research just published papers on several databases that put a wealth of information on various epi-phenomena right at your fingertips. Chances are, at least one of these has info that will make your research life a whole lot easier. HIstome The Histone Infobase (HIstome), […]