Webserver for Aligning Non-Coding RNA Structure-WARJuly 13, 2008Finally a WAR with no conflict. We have to give a big electronic high five to the group from the University of Copenhagen who just introduced a very helpful web utility: WAR-Webserver for aligning structural RNAs is a very handy site that allows you to use the best algorithms for aligning and predicting the consensus […]
Pursuit of the Moving miRNA TargetApril 11, 2008Since 3’ UTRs were found to contain docking sites for miRNAs, labs with computational muscle around the world have been chipping away the target predication dilemma, but like any game, it’s hard to win when you don’t know the rules. It’s even harder when the rules are being rewritten weekly which is why we have […]
RIP it Good: The Rise of Ribonucleicprotein IPApril 5, 2008For years, transcriptional regulation took center stage in studies of gene expression, and the nuances of which transcription factor binds to which DNA sequence under which circumstances dominated the dialogue of molecular biologists. In recent years, a supporting actor has threatened to steal the show: enter, post-transcriptional regulation. The idea that messenger RNA utilization could […]
Espionage, Genetics, and miRNAMarch 12, 2008George Adrian Calin received both his M.D. and Ph.D. degrees at Carol Davila University of Medicine in Bucharest, Romania, where he started cytogenetics work with Dr Dragos Stefanescu. After completing cancer genomics training in Dr. Massimo Negrini’s laboratory at University of Ferrara, Italy, he became a postdoctoral fellow at Kimmel Cancer Center in Philadelphia, PA, […]