Prediction Models Re-Write the Book on Nucleosome Occupancy and miRNA TargetingAugust 23, 2012A pair of newly released papers prove that you don’t always have to run more wet lab experiments to learn something new, you just need to look the data in a different way. The two research groups both used simulations and prediction algorithms, like the ones found on our Epigenetics Databases and Tools list, to […]
Non-Coding RNAs and Drug AddictionJuly 31, 2012Although a lot of behavioral studies are out there on drug addiction, no one really knows how addiction develops at the molecular level. A new review by researchers in Miami describes lots of evidence from more than 80 studies suggesting that non-coding RNAs, such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), might have a […]
RTL-P: Pinpoint 2’-O-methylation in RNAsJuly 31, 2012Yeah, it would be crazy to play hide-and-go-seek with a GPS, night-vision goggles, and a heat-sensing camera. But that’s kind of similar to the pricey, sophisticated laboratory gadgets that researchers currently have to use to spot 2’-O-methylation hiding on RNAs. Now, scientists in China have come up with a much simpler, less expensive way (called […]
Free White Paper: Genome-Wide Analysis of RNA-Protein InteractionsJuly 3, 2012Nowadays, with RNAs interacting with chromatin interacting with DNA methylation marks, researchers are keener than ever to get their gloves dirty with RNA Immunoprecipitation (RIP). If you fit that bill, then you’ll want to check out this white paper authored by Dr. André P. Gerber out of the Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland. […]
NIH Roadmap Epigenomics Program Data ResourceJune 18, 2012Last August, we shared with you some of the great new online resources being developed by the NIH Roadmap Epigenomics Program. Now, the latest issue of Epigenomics, has published an update of all the latest editions, tweaks and refinements they’ve made over the last year. The NIH Roadmap Reference Epigenome Mapping Consortium has created a […]
Exosome miRNAs Tell Liver Damage DetailsJune 18, 2012Sometimes many paths can lead to the same destination, and in the case of liver disease, it’s important for proper treatment to know the exact route that led to problems. New research shows that exosome miRNAs can tell scientists exactly how liver damage was caused. Several things, from chemicals to viruses, can trigger liver damage […]
Ontario Cancer Institute Epigenetic Research PositionsJune 17, 2012News reports tell us how tough the job market is lately, so we’re doing our part for the global economy by posting these two new epigenetic research positions that the Ontario Cancer Institute (OCI) is looking to fill. Who knows? Maybe one of them is perfect for you. Postdoctoral Research Fellow or Research Associates – […]
EZH2, PRC2 Get a Little Guidance From Intronic RNAs to Find Target GenesJune 7, 2012When touring an unfamiliar city or museum, it often helps to have a good guide if you want to see the best sights. Researchers in Spain now report that intronic RNAs, like a well trained herding dog, usher the repressive polycomb complex right to the specific chromatin regions they need to target in order to […]
Epigenetics Book Reviews and Chapter SummariesJune 6, 2012Over the last year EpiGenie has reviewed a couple of the latest epigenetics textbooks for the site. As good citizens of the earth, we of course looked for ways to recycle the books (and the knowledge inside of them) once our writers were done with them. So, we sent our copies out to readers and […]
Conference Trends: Nutrition in EpigeneticsMay 15, 2012Conferences provide an up-to-the-minute look at what’s going on inside epigenetics labs all over the world. By tuning into our conference coverage, we’ve tagged diet and nutrition as an important trend to follow in epigenetic research. Here’s a look at some trendy examples in our Conference Highlights from the last year or so. Differentially Methylated […]