The Epigenetics of T-Cell Development with Dr. Ellen RothenbergDecember 20, 2019Dr. Ellen Rothenberg from the California Institute of Technology discusses her lab’s research into the epigenetics of T-cell development at the 2019 joint CEEHRC/IHEC meeting.
The Epigenomics of Human Health with Dr. John GreallyDecember 20, 2019Dr. John Greally from the Albert Einstein College of Medicine discusses his group’s research into the epigenomics of human health at the 2019 joint CEEHRC/IHEC meeting.
X Chromosome Inactivation with Dr. Carolyn BrownDecember 20, 2019Dr. Carolyn Brown from the University of British Columbia discusses her lab’s research into the epigenetics of X chromosome inactivation at the 2019 joint CEEHRC/IHEC meeting.
Biotechnology Development and Cancer Epigenomics with Dr. Martin HirstDecember 20, 2019Dr. Martin Hirst from the University of British Columbia discusses his lab’s epigenomic research focused on biotechnology development and cancer at the 2019 joint CEEHRC/IHEC meeting.
Sperm Epigenomics and Environmental Exposures with Dr. Sarah KimminsDecember 20, 2019Dr. Sarah Kimmins from McGill University discusses her lab’s research into sperm epigenomics at the 2019 joint CEEHRC/IHEC meeting.
MeCP2 on the Brain: Repressing Transcription of Long Highly Methylated GenesDecember 17, 2019It seems that everyone has MeCP2 on the brain – as evidenced by its starring role in two new Molecular Cell papers – but it’s in your brain too! The MeCP2 protein is essential for neuronal function and consistent with this, loss-of-function mutations in MeCP2 cause the neurodevelopmental disorder Rett syndrome. Unfortunately, because MeCP2 acts […]
Epigenetic Couch Potatoes: Running isn’t on the Resolution Radar of Rodents This Year Thanks to DNA MethylationDecember 11, 2019The year is coming to an end and you know what that means — it’s time to promise yourself that next year is your year to get fit. But if you’re one of the many who never quite live up to their lofty activity goals, don’t be too hard on yourself; your epigenetics may be […]
CpH DNA Methylation Steps Out of the CpG Shadow During Brain DevelopmentNovember 4, 2019DNA methylation and CpG sites just go together, so in fact well that sometimes we forget that DNA methylation can happen in other cytosine contexts too! With new advances in sequencing technologies, non-CpG methylation is stepping out of the shadows and being seen for the important role it plays. DNA methylation is particularly important in […]
Single Cell Analyses Reveal How Epigenetic Drift Makes Stem Cells Age Badly!October 28, 2019While cheese and wine (and whisky!) all get better with age, the human body fares less well! Although partaking in too many culinary delights hardly helps, studies have established the reduced number and activity of stem cells as a cause for the age-related deterioration of various tissue types. With this in mind, a talented team […]
Foretelling Future Hippocampal Transcription and Disease Risk with Early DNA Methylation ProfilesOctober 27, 2019Will it rain tomorrow? Will I ever win the lottery? Will our new paper finally be accepted!? Unfortunately, we have yet to come up with a sturdy means to predict our fates far in the future; however, new research by Hadad and colleagues now suggests that DNA methylation profiles in young cells accurately foretell changes […]
