From A to G: The Ins and Outs of ChIP BeadsSeptember 12, 2012If you don’t run chromatin immunoprecipitation (ChIP) experiments on a daily basis, there’s a good chance that you find the dizzying variety of available immunoprecipitation bead choices a little overwhelming. We asked the ChIP experts from EMD Millipore to help us break down what you need to know about ChIP beads so that you choose […]
EpiGenie Reviews Non-Coding RNAs and Epigenetic Regulation of Gene ExpressionSeptember 11, 2012In recent years, studies exploring the modulation of gene transcription by non-coding RNAs have definitely been on the rise. This book, Non-Coding RNAs and Epigenetic Regulation of Gene Expression, written by a selection of highly regarded scientists, and edited by Kevin Morris, represents an overview and summary of this important new field to date. It’s […]
Splicing up Epigenetics with Dr. Shalini OberdoerfferAugust 23, 2012Dr. Shalini Oberdoerffer covers the role of splicing in epigenetics, how splicing and DNA methylation affect exon definition and the crosstalk between nucleosome and splicing mechanisms. Splicing Up Epigenetics In the splicing field several years ago, it was a somewhat surprising study coming out of whole genome sequencing studies of ChIP-seq data wherein it […]
Redefining DNA Methylation in Cancer with Dr. Andrew FeinbergAugust 1, 2012Dr. Andrew Feinberg discusses how recent events are reshaping the way his team thinks about DNA methylation in cancer. This interview was shot on campus at Johns Hopkins University. This video was brought to you by epigenetics supporters at EMD Millipore. Redefining DNA Methylation in Cancer Well, there are a number of things I’m […]
Guide: Quick Tips for ChIP BeginnersJuly 17, 2012 At Abcam we run quite a few ChIP assays and we interact with customers that run even more than us. Lately, we’ve noticed that more researchers are turning to ChIP for the first time as gene regulation studies continue to grow. So we thought we’d share a couple of quick tips for various aspects of […]
Pushing the Technology Frontier in Epigenetics Research with Dr. Andrew FeinbergJuly 16, 2012Dr. Andy Feinberg discusses what technology advances are needed in the field of epigenetics. This interview was shot on campus at Johns Hopkins University. This video was brought to you by epigenetics supporters at EMD Millipore Single Cell Analysis One of the areas I think is going to be really important is single-cell analysis. […]
Step Up Your Bisulfite: DNA Methylation Analysis Tips for Challenging SamplesJuly 11, 2012Sooner or later researchers studying DNA methylation turn it up a notch and get into some difficult sample scenarios, where the interesting data hides tucked away. We caught up with the R&D scientists at Zymo Research to hear more about some of the challenges that researchers face when stepping up into some of these sample […]
New Epigenetic Analysis Methods to Watch in 2012May 24, 2012Based on what we’ve seen so far in journals, conferences and interviews, 2012 could be a banner year for epigenetic analysis methods. New twists on old tricks, and futuristic technology advances have converged to create some really exciting new approaches in the field. Here are just a few that you’ll want to keep track of […]
Single Molecule Epigenetic Analysis with Dr. Paul SolowayMay 15, 2012Dr. Paul Soloway discusses the limitations with some of the main methods used in epigenetics research and shares a glimpse into what the next generation of tools will look like. This interview took place at the Keystone Symposia’s Epigenomics and Chromatin Dynamics joint meeting in January, 2012. Getting Past ChIP and Bisulfite Applications So, chromatin […]
Conference Trends: Nutrition in EpigeneticsMay 15, 2012Conferences provide an up-to-the-minute look at what’s going on inside epigenetics labs all over the world. By tuning into our conference coverage, we’ve tagged diet and nutrition as an important trend to follow in epigenetic research. Here’s a look at some trendy examples in our Conference Highlights from the last year or so. Differentially Methylated […]